Hydroxylamine → 2-(5-bromo-4-(1-cyclopropylnaphthalen-4-yl)-4H-1,2,4-triazol-3-ylthio)-N-hydroxyacetamide

HRID 1208420Notes

Reaction equation

HRID 1208420 reaction equation
[Br:1][c:2]1[n:3](-[c:12]2[cH:13][cH:14][c:15]([CH:22]3[CH2:23][CH2:24]3)[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]23)[c:4]([S:7][CH2:8][C:9](=[O:10])[OH:11])[n:5][n:6]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:35][OH:36].[NH2:27][OH:28].[Na+:26].[OH-:25].[OH2:29]>>[Br:1][c:2]1[n:3](-[c:12]2[cH:13][cH:14][c:15]([CH:22]3[CH2:23][CH2:24]3)[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]23)[c:4]([S:7][CH2:8][C:9](=[O:11])[NH:27][OH:25])[n:5][n:6]1

Participants

8

Reactant 7

HCID 787HydroxylamineHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 53465279Lesinurad

Product 1

HCID 578113102-(5-bromo-4-(1-cyclopropylnaphthalen-4-yl)-4H-1,2,4-triazol-3-ylthio)-N-hydroxyacetamide

Sources & evidence

ORD record
ord-5619e143cb8d4e6a87c340fdb8172627
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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