Tetrahydrofuran → ethyl 1-(4-methanesulfonylaminophenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxylate

HRID 120847Notes

Reaction equation

HRID 120847 reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:1][S:2]([Cl:3])(=[O:4])=[O:5].[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[NH2:6][c:7]1[cH:8][cH:9][c:10](-[n:13]2[n:14][cH:15][c:16]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:17]2[C:18]([F:19])([F:20])[F:21])[cH:11][cH:12]1>>[CH3:1][S:2](=[O:4])(=[O:5])[NH:6][c:7]1[cH:8][cH:9][c:10](-[n:13]2[n:14][cH:15][c:16]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:17]2[C:18]([F:19])([F:20])[F:21])[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 2808376Ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate

Product 1

HCID 22288382ethyl 1-(4-methanesulfonylaminophenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxylate

Sources & evidence

ORD record
ord-9f7bff48a08b4a7692e75bce07861aa8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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