Ammonium → 3-(1-Adamantylamino)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one

HRID 1209594Notes

Reaction equation

HRID 1209594 reaction equation
[Br:1][c:2]1[c:3](=[O:20])[n:4](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:5][c:6](-[c:8]2[n:9][cH:10][cH:11][cH:12][cH:13]2)[cH:7]1.[C:21]12([NH2:31])[CH2:22][CH:23]3[CH2:24][CH:25]([CH2:26][CH:27]([CH2:28]1)[CH2:29]3)[CH2:30]2.[CH3:36][N:37]([CH3:38])[CH:39]=[O:40].[Cl-:34].[H-:32].[NH4+:35].[Na+:33].[OH2:41]>>[c:2]1([NH:31][C:21]23[CH2:22][CH:23]4[CH2:24][CH:25]([CH2:26][CH:27]([CH2:28]2)[CH2:29]4)[CH2:30]3)[c:3](=[O:20])[n:4](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:5][c:6](-[c:8]2[n:9][cH:10][cH:11][cH:12][cH:13]2)[cH:7]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 923Sodium ionHCID 962WaterHCID 2130AmantadineHCID 6228DimethylformamideHCID 166653HydrideHCID 223190653-Bromo-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one

Product 1

HCID 223189373-(1-Adamantylamino)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one

Sources & evidence

ORD record
ord-1ce25722d2384de4938ff7094a933d7f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…