Hydrochloric Acid → 2-(isopropoxymethyl)-N-(4-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine
Reaction equation
[CH:35]([CH3:36])([CH3:37])[OH:38].[Cl:2][CH2:3][c:4]1[n:5][c:6]2[cH:7][c:8](-[c:25]3[n:26][cH:27][cH:28][cH:29][c:30]3[C:31]([F:32])([F:33])[F:34])[cH:9][cH:10][c:11]2[c:12]([NH:14][c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:13]1.[ClH:1]>>[CH2:3]([c:4]1[n:5][c:6]2[cH:7][c:8](-[c:25]3[n:26][cH:27][cH:28][cH:29][c:30]3[C:31]([F:32])([F:33])[F:34])[cH:9][cH:10][c:11]2[c:12]([NH:14][c:15]2[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[n:13]1)[O:38][CH:35]([CH3:36])[CH3:37]Participants
4
Sources & evidence
- ORD record
- ord-f65d2f2fc2b94b4fa88533b70d061b09
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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