Dimethylformamide → tert-Butyl 2-(5-formylthiophene-2-carboxamido)phenylcarbamate

HRID 1209841Notes

Reaction equation

HRID 1209841 reaction equation
[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([C:8](=[O:9])[OH:10])[s:7]1.[NH2:11][c:12]1[c:13]([NH:18][C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[cH:14][cH:15][cH:16][cH:17]1.[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([C:8](=[O:10])[NH:11][c:12]2[c:13]([NH:18][C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[cH:14][cH:15][cH:16][cH:17]2)[s:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 676311N-(tert-Butoxycarbonyl)-1,2-phenylenediamineHCID 8188825-Formyl-2-thiophenecarboxylic Acid

Product 1

HCID 58930645tert-Butyl 2-(5-formylthiophene-2-carboxamido)phenylcarbamate

Sources & evidence

ORD record
ord-ceb9fe3977f146618c9f9b8ff1a68a6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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