Chloride → tert-Butyl 3-acetylazetidine-1-carboxylate

HRID 1210167Notes

Reaction equation

HRID 1210167 reaction equation
[CH3:1][O:2][N:3]([C:4](=[O:5])[CH:6]1[CH2:7][N:8]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:9]1)[CH3:17].[CH3:24][Mg+:25].[Cl-:23].[O:18]1[CH2:19][CH2:22][CH2:21][CH2:20]1.[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[C:4](=[O:5])([CH:6]1[CH2:7][N:8]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:9]1)[CH3:19]

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028Tetrahydrofuran2×HCID 21306970tert-Butyl 3-(methoxy(methyl)carbamoyl)azetidine-1-carboxylateHCID 178477777HCID 178477777, compound

Product 1

HCID 59841137tert-Butyl 3-acetylazetidine-1-carboxylate

Sources & evidence

ORD record
ord-b8a60df048944e2ab029bc4de889f400
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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