Acetate → (+/-)-{8-[(4-Fluoro-benzenesulfonyl)-methyl-amino]6,7,8,9-tetrahydro-pyrido[3,2-b]indolizin-5-yl}-acetic acid methyl ester

HRID 1210185Notes

Reaction equation

HRID 1210185 reaction equation
[CH3:30][I:31].[CH3:33][C:34](=[O:35])[O-:36].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[F:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[CH2:13][n:14]3[c:15]4[c:16]([c:17]([CH2:21][C:22](=[O:23])[O:24][CH3:25])[c:18]3[CH2:19][CH2:20]2)[cH:26][cH:27][cH:28][n:29]4)[cH:6][cH:7]1.[NH4+:32].[O:43]=[CH:44][N:45]([CH3:46])[CH3:47]>>[F:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[CH2:13][n:14]3[c:15]4[c:16]([c:17]([CH2:21][C:22](=[O:23])[O:24][CH3:25])[c:18]3[CH2:19][CH2:20]2)[cH:26][cH:27][cH:28][n:29]4)[CH3:33])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 175AcetateHCID 223AmmoniumHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 8857Ethyl AcetateHCID 178499379HCID 178499379, compound

Product 1

HCID 59471440(+/-)-{8-[(4-Fluoro-benzenesulfonyl)-methyl-amino]6,7,8,9-tetrahydro-pyrido[3,2-b]indolizin-5-yl}-acetic acid methyl ester

Sources & evidence

ORD record
ord-eb3214f2776f41ebbdeba8a76af38f51
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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