Tetrahydrofuran → 1-(4-bromo-2-methylsulfonylphenyl)-N-[[5-fluoro-2-(2-methoxyethoxy)phenyl]methyl]methanamine

HRID 1210281Notes

Reaction equation

HRID 1210281 reaction equation
[Br:1][c:2]1[cH:3][c:4]([S:10](=[O:11])(=[O:12])[CH3:13])[c:5]([CH2:6][NH2:7])[cH:8][cH:9]1.[Br:21][CH2:22][c:23]1[c:24]([O:30][CH2:31][CH2:32][O:33][CH3:34])[cH:25][cH:26][c:27]([F:29])[cH:28]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20]>>[Br:1][c:2]1[cH:3][c:4]([S:10](=[O:11])(=[O:12])[CH3:13])[c:5]([CH2:6][NH:7][CH2:22][c:23]2[c:24]([O:30][CH2:31][CH2:32][O:33][CH3:34])[cH:25][cH:26][c:27]([F:29])[cH:28]2)[cH:8][cH:9]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 226199942-(Bromomethyl)-4-fluoro-1-(2-methoxyethoxy)benzeneHCID 22620001(4-Bromo-2-methylsulfonylphenyl)methanamine

Product 1

HCID 226200021-(4-bromo-2-methylsulfonylphenyl)-N-[[5-fluoro-2-(2-methoxyethoxy)phenyl]methyl]methanamine

Sources & evidence

ORD record
ord-2c86f457b2284e8eb834a7a82fd288e0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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