Dimethylformamide → N-(6-Chloro-pyridin-3-yl)-2-(7-fluoro-1-oxo-1,2,3,10-tetrahydro-azepino[3,4-b]indol-5-yl)-acetamide

HRID 1210428Notes

Reaction equation

HRID 1210428 reaction equation
[CH:21]([N:22]([CH2:23][CH3:24])[CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[Cl:54][c:55]1[cH:56][cH:57][c:58]([NH2:61])[cH:59][n:60]1.[F:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([nH:7][c:8]2[cH:9][cH:10]1)[C:11](=[O:20])[NH:12][CH2:13][CH:14]=[C:15]3[CH2:16][C:17](=[O:18])[OH:19].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[P-:30]([F:31])([F:32])([F:33])([F:34])([F:35])[F:36].[n:37]1([O:38][C:39]([N:40]([CH3:41])[CH3:42])=[N+:43]([CH3:44])[CH3:45])[c:46]2[n:47][cH:48][cH:49][cH:50][c:51]2[n:52][n:53]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([nH:7][c:8]2[cH:9][cH:10]1)[C:11](=[O:20])[NH:12][CH2:13][CH:14]=[C:15]3[CH2:16][C:17](=[O:19])[NH:61][c:58]1[cH:57][cH:56][c:55]([Cl:54])[n:60][cH:59]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 793055-Amino-2-chloropyridineHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 59789203(7-Fluoro-1-oxo-1,2,3,10-tetrahydro-azepino[3,4-b]indol-5-yl)-acetic acid

Product 1

HCID 59789199N-(6-Chloro-pyridin-3-yl)-2-(7-fluoro-1-oxo-1,2,3,10-tetrahydro-azepino[3,4-b]indol-5-yl)-acetamide

Sources & evidence

ORD record
ord-3c76d76b201145019abdd2c6a3290a9b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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