Potassium Cation → [2-(3-Chloro-phenoxy)-5-fluoro-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone

HRID 121045Notes

Reaction equation

HRID 121045 reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[CH3:35][C:36]#[N:37].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:20])[cH:6][c:7]1[C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21.[Cl:21][c:22]1[cH:23][c:24]([OH:28])[cH:25][cH:26][cH:27]1.[Cu:38][I:39].[Cu:40].[K+:33].[K+:34]>>[c:2]1([O:28][c:24]2[cH:23][c:22]([Cl:21])[cH:27][cH:26][cH:25]2)[n:3][cH:4][c:5]([F:20])[cH:6][c:7]1[C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 79333-ChlorophenolHCID 19660Carbonate IonHCID 23978CopperHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 86641254(2-Chloro-5-fluoro-pyridin-3-yl)-(3,4-dihydro-2H-quinolin-1-yl)-methanone

Product 1

HCID 46195846[2-(3-Chloro-phenoxy)-5-fluoro-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone

Sources & evidence

ORD record
ord-4c3d8a904ccf4a59862e6a72211b5815
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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