Dimethylformamide → tert-Butyl 2-cyanopyrrolidine-1-carboxylate

HRID 1210967Notes

Reaction equation

HRID 1210967 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:13]([NH2:14])=[O:15])[CH2:10][CH2:11][CH2:12]1.[Cl:16][c:17]1[n:18][c:19]([Cl:20])[n:21][c:22]([Cl:23])[n:24]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:13]#[N:14])[CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 7954Cyanuric chlorideHCID 30168861,1-Dimethylethyl 2-(aminocarbonyl)-1-pyrrolidinecarboxylate

Product 1

HCID 2756786tert-Butyl 2-cyanopyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-e187d6f4f9494e7895290e1d9357c461
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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