Potassium Cation → 5-chloro-N-[[4-chloro-3-[3-chloro-5-(2-cyanoethenyl)phenoxy]-2-fluorophenyl]methyl]-3-(2-trimethylsilylethoxymethyl)imidazole-4-carboxamide

HRID 1211364Notes

Reaction equation

HRID 1211364 reaction equation
[C:1](#[N:2])[CH2:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[O:9][CH2:10][CH3:11].[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:12][C:13]([CH3:14])([O-:15])[CH3:16].[CH3:59][CH2:60][O:61][C:62]([CH3:63])=[O:64].[Cl:18][c:19]1[n:20][cH:21][n:22]([CH2:46][O:47][CH2:48][CH2:49][Si:50]([CH3:51])([CH3:52])[CH3:53])[c:23]1[C:24](=[O:25])[NH:26][CH2:27][c:28]1[c:29]([F:45])[c:30]([O:35][c:36]2[cH:37][c:38]([Cl:44])[cH:39][c:40]([CH:42]=[O:43])[cH:41]2)[c:31]([Cl:34])[cH:32][cH:33]1.[K+:17]>>[C:1](#[N:2])[CH:3]=[CH:42][c:40]1[cH:39][c:38]([Cl:44])[cH:37][c:36]([O:35][c:30]2[c:29]([F:45])[c:28]([CH2:27][NH:26][C:24]([c:23]3[c:19]([Cl:18])[n:20][cH:21][n:22]3[CH2:46][O:47][CH2:48][CH2:49][Si:50]([CH3:51])([CH3:52])[CH3:53])=[O:25])[cH:33][cH:32][c:31]2[Cl:34])[cH:41]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 75676Diethyl (cyanomethyl)phosphonateHCID 45749132-Methylpropan-2-olateHCID 866449404-chloro-N-({4-chloro-3-[(3-chloro-5-formylphenyl)oxy]-2-fluorophenyl}methyl)-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamide

Product 1

HCID 684855805-chloro-N-[[4-chloro-3-[3-chloro-5-(2-cyanoethenyl)phenoxy]-2-fluorophenyl]methyl]-3-(2-trimethylsilylethoxymethyl)imidazole-4-carboxamide

Sources & evidence

ORD record
ord-312ab308ba654e71a8204b901b69d77d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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