Hydroxide → [3-(2,6-Dichloro-5-isopropyl-pyrimidin-4-yloxy)-5-methyl-phenyl]-methanol

HRID 1212103Notes

Reaction equation

HRID 1212103 reaction equation
[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[Cl:1][c:2]1[n:3][c:4]([Cl:24])[c:5]([CH:21]([CH3:22])[CH3:23])[c:6]([O:8][c:9]2[cH:10][c:11]([CH2:12][O:13][C:14](=[O:15])[CH3:16])[cH:17][c:18]([CH3:20])[cH:19]2)[n:7]1.[Li+:25].[OH-:26]>>[Cl:1][c:2]1[n:3][c:4]([Cl:24])[c:5]([CH:21]([CH3:22])[CH3:23])[c:6]([O:8][c:9]2[cH:10][c:11]([CH2:12][OH:13])[cH:17][c:18]([CH3:20])[cH:19]2)[n:7]1

Participants

5

Reactant 4

HCID 961HydroxideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 59184647Acetic acid 3-(2,6-dichloro-5-isopropyl-pyrimidin-4-yloxy)-5-methyl-benzyl ester

Product 1

HCID 59184707[3-(2,6-Dichloro-5-isopropyl-pyrimidin-4-yloxy)-5-methyl-phenyl]-methanol

Sources & evidence

ORD record
ord-f89d73993fef4c519dfcdffae0419a74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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