Dimethylformamide → 3'-(2,2-dimethylpropoxy)-7'-[2-(3-methyloxetan-3-yl)ethynyl]spiro[5H-1,3-oxazole-4,5'-chromeno[2,3-b]pyridine]-2-amine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:19]([cH:20][cH:21]1)[O:18][c:7]1[c:6]([cH:11][c:10]([O:12][CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:9][n:8]1)[C:5]21[N:22]=[C:23]([NH2:26])[O:24][CH2:25]1.[CH3:39][Si:40]([C:41]#[C:42][C:43]1([CH3:47])[CH2:44][O:45][CH2:46]1)([CH3:48])[CH3:49].[CH:32]([NH:33][CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cu:50]([I:51])[I:52].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[cH:53]1[cH:54][cH:55][c:56]([P:57]([Pd:58]([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([P:78]([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[P:97]([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)([c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)[cH:128][cH:129]1>>[c:2]1([C:41]#[C:42][C:43]2([CH3:47])[CH2:44][O:45][CH2:46]2)[cH:3][c:4]2[c:19]([cH:20][cH:21]1)[O:18][c:7]1[c:6]([cH:11][c:10]([O:12][CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:9][n:8]1)[C:5]21[N:22]=[C:23]([NH2:26])[O:24][CH2:25]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e1ea5f50760043aa8103087ae59e9d80
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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