Tetrahydrofuran → 4-(1-Hydroxycyclobutyl)benzonitrile
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[C:15]1(=[O:19])[CH2:16][CH2:17][CH2:18]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1>>[c:2]1([C:15]2([OH:19])[CH2:16][CH2:17][CH2:18]2)[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1Participants
5
Sources & evidence
- ORD record
- ord-321d0c2141194110816ac410a47ade5b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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