Tetrahydrofuran → 1-(3,3-difluorocyclobutyl)-N,N-dimethylmethanamine
Reaction equation
[Al+3:13].[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1.[F:1][C:2]1([F:11])[CH2:3][CH:4]([C:6](=[O:7])[N:8]([CH3:9])[CH3:10])[CH2:5]1.[H-:12].[H-:15].[H-:16].[H-:17].[Li+:14]>>[F:1][C:2]1([F:11])[CH2:3][CH:4]([CH2:6][N:8]([CH3:9])[CH3:10])[CH2:5]1Participants
6
Sources & evidence
- ORD record
- ord-b8d3969cb72f40e19eec53fe62d894f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…