Hydrochloric Acid → N-[(1RS,2SR)-1-(4-tert-butoxybenzyl)-2-(3-chlorophenyl)-2-hydroxyethyl]-4-fluoro-1-naphthamide
Reaction equation
[CH2:39]([N:40]=[C:41]=[N:42][CH2:43][CH2:44][CH2:45][N:46]([CH3:47])[CH3:48])[CH3:49].[CH3:61][C:62]#[N:63].[ClH:38].[F:24][c:25]1[cH:26][cH:27][c:28]([C:35](=[O:36])[OH:37])[c:29]2[cH:30][cH:31][cH:32][cH:33][c:34]12.[NH2:1][CH:2]([CH:3]([OH:4])[c:5]1[cH:6][c:7]([Cl:11])[cH:8][cH:9][cH:10]1)[CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:17][cH:18]1.[OH2:50].[OH2:64].[OH:51][n:52]1[c:53]2[cH:54][cH:55][cH:56][cH:57][c:58]2[n:59][n:60]1>>[NH:1]([CH:2]([CH:3]([OH:4])[c:5]1[cH:6][c:7]([Cl:11])[cH:8][cH:9][cH:10]1)[CH2:12][c:13]1[cH:14][cH:15][c:16]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[cH:17][cH:18]1)[C:35]([c:28]1[cH:27][cH:26][c:25]([F:24])[c:34]2[c:29]1[cH:30][cH:31][cH:32][cH:33]2)=[O:36]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-d7b6058791834574ac76be08f7885af4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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