Hydrochloric Acid → 5-Bromo-6-fluoro-indole-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[cH:9][c:10]1[F:11].[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23]([O:24][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:25].[CH3:12][C:13]([CH3:14])([O-:15])[CH3:16].[ClH:30].[K+:17].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH2:36]>>[Br:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][n:7]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[c:8]2[cH:9][c:10]1[F:11]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-04e9936ebbcc425489b0e1ad786e5c1b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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