HRID1214454

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID961

Hydroxide

HO-

HCID962

Water

H2O

HCID6344

Dichloromethane

CH2Cl2

HCID8471

Triethylamine

C6H15N

HCID28486

Lithium ion

Li+

HCID152842

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride

C6H8ClN2O5P

HCID570891

6-Methoxypicolinic acid

C7H7NO3

HCID60205276

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(C(=O)Nc2c[nH]c3ncc(Br)c(F)c23)n1

HCID60205376

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-53fc492d53354262b513d951c42762fa
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (5/10)

反应 SMILES

[Br:1][c:2]1[c:3]([F:12])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH2:11].[CH3:13][O:14][c:15]1[cH:16][cH:17][cH:18][c:19]([C:21](=[O:22])[OH:23])[n:20]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[Cl:48][CH2:49][Cl:50].[Li+:47].[O:24]=[C:25]1[N:26]([P:27]([Cl:28])([N:29]2[CH2:30][CH2:31][O:32][C:33]2=[O:34])=[O:35])[CH2:36][CH2:37][O:38]1.[OH-:46].[OH2:51]>>[Br:1][c:2]1[c:3]([F:12])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:21]([c:19]1[cH:18][cH:17][cH:16][c:15]([O:14][CH3:13])[n:20]1)=[O:22]