Hydroxide → N-(5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-6-methoxypicolinamide
Reaction equation
[Br:1][c:2]1[c:3]([F:12])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH2:11].[CH3:13][O:14][c:15]1[cH:16][cH:17][cH:18][c:19]([C:21](=[O:22])[OH:23])[n:20]1.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[Cl:48][CH2:49][Cl:50].[Li+:47].[O:24]=[C:25]1[N:26]([P:27]([Cl:28])([N:29]2[CH2:30][CH2:31][O:32][C:33]2=[O:34])=[O:35])[CH2:36][CH2:37][O:38]1.[OH-:46].[OH2:51]>>[Br:1][c:2]1[c:3]([F:12])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:21]([c:19]1[cH:18][cH:17][cH:16][c:15]([O:14][CH3:13])[n:20]1)=[O:22]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-53fc492d53354262b513d951c42762fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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