Pyridine → 4-Chloro-2-{[2-(2-chloro-3,6-difluoro-phenyl)-acetyl]-methyl-amino}-6-methyl-nicotinic acid ethyl ester
Reaction equation
[CH2:25]([CH3:26])[O:27][C:28]([c:29]1[c:30]([NH:37][CH3:38])[n:31][c:32]([CH3:36])[cH:33][c:34]1[Cl:35])=[O:39].[CH3:20][N:21]([CH3:22])[CH:23]=[O:24].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:40][CH2:41][Cl:42].[Cl:7][c:8]1[c:9]([CH2:16][C:17](=[O:18])[OH:19])[c:10]([F:15])[cH:11][cH:12][c:13]1[F:14].[cH:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1>>[Cl:7][c:8]1[c:9]([CH2:16][C:17](=[O:19])[N:37]([c:30]2[c:29]([C:28]([O:27][CH2:25][CH3:26])=[O:39])[c:34]([Cl:35])[cH:33][c:32]([CH3:36])[n:31]2)[CH3:38])[c:10]([F:15])[cH:11][cH:12][c:13]1[F:14]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-669833c8b9e349feab0fb93d5a776c29
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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