Hydrochloric Acid → 1-[2-Fluoro-4-(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yloxy)phenylcarbamoyl]cyclopropanecarboxylic acid
Reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][C:10](=[O:11])[C:12]1([C:15]([NH:16][c:17]2[c:18]([F:46])[cH:19][c:20]([O:23][c:24]3[cH:25][c:26]([NH:30][C:31](=[O:32])[N:33]4[CH2:34][CH2:35][CH:36]([N:39]5[CH2:40][CH2:41][N:42]([CH3:45])[CH2:43][CH2:44]5)[CH2:37][CH2:38]4)[n:27][cH:28][cH:29]3)[cH:21][cH:22]2)=[O:47])[CH2:13][CH2:14]1.[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[ClH:1].[Na+:49].[OH-:48].[OH2:50]>>[O:9]=[C:10]([OH:11])[C:12]1([C:15]([NH:16][c:17]2[c:18]([F:46])[cH:19][c:20]([O:23][c:24]3[cH:25][c:26]([NH:30][C:31](=[O:32])[N:33]4[CH2:34][CH2:35][CH:36]([N:39]5[CH2:40][CH2:41][N:42]([CH3:45])[CH2:43][CH2:44]5)[CH2:37][CH2:38]4)[n:27][cH:28][cH:29]3)[cH:21][cH:22]2)=[O:47])[CH2:13][CH2:14]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-15b13c2f98914592b2c5b8df9c763e42
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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