Toluene → 1-(2-Chloro-9,10-dihydro-9,10-methanoanthracen-9-ylcarbonyl)piperidin-4-ol

HRID 1215704Notes

Reaction equation

HRID 1215704 reaction equation
[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH3:38][CH2:39][O:40][C:41](=[O:42])[CH3:43].[Cl:1][c:2]1[cH:3][c:4]2[c:13]([cH:14][cH:15]1)[CH:12]1[c:11]3[c:6]([cH:7][cH:8][cH:9][cH:10]3)[C:5]2([C:17](=[O:18])[OH:19])[CH2:16]1.[OH:24][CH:25]1[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1.[S:20]([Cl:21])([Cl:22])=[O:23]>>[Cl:1][c:2]1[cH:3][c:4]2[c:13]([cH:14][cH:15]1)[CH:12]1[c:11]3[c:6]([cH:7][cH:8][cH:9][cH:10]3)[C:5]2([C:17](=[O:18])[N:28]2[CH2:27][CH2:26][CH:25]([OH:24])[CH2:30][CH2:29]2)[CH2:16]1

Participants

6

Reactant 5

HCID 1140TolueneHCID 8857Ethyl AcetateHCID 24386Thionyl ChlorideHCID 79341Piperidin-4-olHCID 196986472-Chloro-9,10-dihydro-9,10-methano-9-anthracenecarboxylic acid

Product 1

HCID 214806421-(2-Chloro-9,10-dihydro-9,10-methanoanthracen-9-ylcarbonyl)piperidin-4-ol

Sources & evidence

ORD record
ord-fbbc5c48c56e40b08e7fbabef076d5a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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