1,2-Dibromoethane → tert-butyl 5-[1-hydroxy-4-methyl-3-(phenylmethoxymethyl)pentyl]-2-[4-methoxy-3-(3-methoxypropoxy)phenyl]-3-propan-2-ylpyrrolidine-1-carboxylate
Reaction equation
[Br:48][CH2:49][CH2:50][Br:51].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:18]2[cH:19][c:20]([O:26][CH2:27][CH2:28][CH2:29][O:30][CH3:31])[c:21]([O:24][CH3:25])[cH:22][cH:23]2)[CH:10]([CH:15]([CH3:16])[CH3:17])[CH2:11][CH:12]1[CH:13]=[O:14].[Cl:32][CH2:33][CH:34]([CH2:35][O:36][CH2:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)[CH:44]([CH3:45])[CH3:46].[Mg:47].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([c:18]2[cH:19][c:20]([O:26][CH2:27][CH2:28][CH2:29][O:30][CH3:31])[c:21]([O:24][CH3:25])[cH:22][cH:23]2)[CH:10]([CH:15]([CH3:16])[CH3:17])[CH2:11][CH:12]1[CH:13]([OH:14])[CH2:33][CH:34]([CH2:35][O:36][CH2:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)[CH:44]([CH3:45])[CH3:46]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d7977069dbc6414db516683aeb394058
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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