Dichloromethane → Trifluoroacetic acid

HRID 1216599Notes

Reaction equation

HRID 1216599 reaction equation
[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[Cl:49][CH2:50][Cl:51].[Cl:8][c:9]1[cH:10][cH:11][c:12]([C:13](=[O:14])[N:15]2[CH2:16][C:17](=[O:30])[N:18]([CH2:26][C:27](=[O:28])[OH:29])[c:19]3[c:20]([cH:22][cH:23][cH:24][cH:25]3)[CH2:21]2)[cH:31][cH:32]1.[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH2:33][CH2:34][CH2:35][c:36]1[n:37][cH:38][cH:39][cH:40][cH:41]1>>[Cl:8][c:9]1[cH:10][cH:11][c:12]([C:13](=[O:14])[N:15]2[CH2:16][C:17](=[O:30])[N:18]([CH2:26][C:27](=[O:28])[NH:33][CH2:34][CH2:35][c:36]3[n:37][cH:38][cH:39][cH:40][cH:41]3)[c:19]3[c:20]([cH:22][cH:23][cH:24][cH:25]3)[CH2:21]2)[cH:31][cH:32]1.[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7]

Participants

7

Reactant 5

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 8471TriethylamineHCID 759192-PyridineethanamineHCID 22632477HCID 22632477, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 22632718HCID 22632718, compound

Sources & evidence

ORD record
ord-00b22b3855a84f4ea4ee9217597c9613
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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