Dimethylformamide → 2-Butyl-5-(3-chlorophenyl)-4-[(4-morpholin-4-ylphenyl)amino]isothiazol-3(2H)-one 1,1-dioxide

HRID 1217001Notes

Reaction equation

HRID 1217001 reaction equation
[CH2:14]([CH2:15][CH2:16][CH3:17])[N:18]1[S:19](=[O:32])(=[O:33])[C:20]([c:25]2[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]2)=[C:21]([Cl:24])[C:22]1=[O:23].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([NH2:11])[cH:12][cH:13]2)[CH2:5][CH2:6]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([NH:11][C:21]3=[C:20]([c:25]4[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]4)[S:19](=[O:32])(=[O:33])[N:18]([CH2:14][CH2:15][CH2:16][CH3:17])[C:22]3=[O:23])[cH:12][cH:13]2)[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 686616252-Butyl-4-chloro-5-(3-chlorophenyl)isothiazol-3(2H)-one 1,1-dioxide

Product 1

HCID 116342902-Butyl-5-(3-chlorophenyl)-4-[(4-morpholin-4-ylphenyl)amino]isothiazol-3(2H)-one 1,1-dioxide

Sources & evidence

ORD record
ord-6e8b0e8ab27740cfa363435b7aafceed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…