Piperazine → Tert-butyl 3-(5-phenyl-1,3,4-oxadiazol-2-yl)-5-(piperazin-1-yl)pyrazin-2-ylcarbamate

HRID 1217267Notes

Reaction equation

HRID 1217267 reaction equation
[Br:1][c:2]1[n:3][c:4](-[c:16]2[o:17][c:18](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[n:19][n:20]2)[c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[n:6][cH:7]1.[CH2:27]1[CH2:28][NH:29][CH2:30][CH2:31][NH:32]1.[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[c:2]1([N:29]2[CH2:28][CH2:27][NH:32][CH2:31][CH2:30]2)[n:3][c:4](-[c:16]2[o:17][c:18](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[n:19][n:20]2)[c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 4837PiperazineHCID 6228DimethylformamideHCID 86662071Tert-butyl 5-bromo-3-(5-phenyl-1,3,4-oxadiazol-2-yl)pyrazin-2-ylcarbamate

Product 1

HCID 66745759Tert-butyl 3-(5-phenyl-1,3,4-oxadiazol-2-yl)-5-(piperazin-1-yl)pyrazin-2-ylcarbamate

Sources & evidence

ORD record
ord-93d2398945a747e6821965dc3fc384c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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