Water → Ethyl 4-chloro-2-(methylthio)-5-oxo-8-phenyl-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-6-carboxylate

HRID 1217451Notes

Reaction equation

HRID 1217451 reaction equation
[CH3:30][CH:31]([N-:32][CH:33]([CH3:34])[CH3:35])[CH3:36].[Cl:1][c:2]1[n:3][c:4]([S:27][CH3:28])[n:5][c:6]([N:13]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:20][CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:7]1[C:8](=[O:9])[O:10][CH2:11][CH3:12].[Li+:29].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[OH2:37]>>[Cl:1][c:2]1[n:3][c:4]([S:27][CH3:28])[n:5][c:6]2[c:7]1[C:8](=[O:9])[CH:21]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[CH2:20][N:13]2[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 59506511HCID 59506511, compound

Product 1

HCID 59506342Ethyl 4-chloro-2-(methylthio)-5-oxo-8-phenyl-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-6-carboxylate

Sources & evidence

ORD record
ord-2de4bcdc5eef4a369ab095964f777e43
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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