Potassium Cation → 6-(4-Bromo-2-chloro-phenylamino)-3-(2-tert-butoxycarbonyl-ethyl)-7-fluoro-3H-benzoimidazole-5-carboxylic acid methyl ester

HRID 1217887Notes

Reaction equation

HRID 1217887 reaction equation
[C:30]([CH:31]=[CH2:32])(=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38].[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][cH:10][nH:11]2)[c:12]([F:23])[c:13]1[NH:14][c:15]1[c:16]([Cl:22])[cH:17][c:18]([Br:21])[cH:19][cH:20]1.[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[K+:24].[K+:25].[O-:26][C:27]([O-:28])=[O:29].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][cH:10][n:11]2[CH2:32][CH2:31][C:30](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[c:12]([F:23])[c:13]1[NH:14][c:15]1[c:16]([Cl:22])[cH:17][c:18]([Br:21])[cH:19][cH:20]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 15458tert-Butyl acrylateHCID 19660Carbonate IonHCID 11749905Methyl 6-((4-bromo-2-chlorophenyl)amino)-7-fluoro-1H-benzo[d]imidazole-5-carboxylate

Product 1

HCID 668866626-(4-Bromo-2-chloro-phenylamino)-3-(2-tert-butoxycarbonyl-ethyl)-7-fluoro-3H-benzoimidazole-5-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-2a4e285ce0f447fb85f0f811fba0587e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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