Chloride → 5-Bromo-6-(2,2,2-trifluoroethoxy)-pyridin-3-ylamine

HRID 1218139Notes

Reaction equation

[Br:1][c:2]1[c:3]([O:11][CH2:12][C:13]([F:14])([F:15])[F:16])[n:4][cH:5][c:6]([N+:8]([O-:9])=[O:10])[cH:7]1.[CH3:19][CH2:20][OH:21].[Cl-:18].[ClH:17]>>[Br:1][c:2]1[c:3]([O:11][CH2:12][C:13]([F:14])([F:15])[F:16])[n:4][cH:5][c:6]([NH2:8])[cH:7]1

Participants

Reactant 4

HCID 312Chloride

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 534077653-Bromo-5-nitro-2-(2,2,2-trifluoroethoxy)pyridine

Product 1

HCID 672810445-Bromo-6-(2,2,2-trifluoroethoxy)-pyridin-3-ylamine

Sources & evidence

ORD record: ord-5ed2131311e843debf65357d86f9860d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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