Hydrogen Peroxide → 2-[4-(1-hydroxypropan-2-yl)phenyl]-N-[1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide

HRID 1218321Notes

Reaction equation

HRID 1218321 reaction equation
[BH3:33].[C:1](=[CH2:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([CH2:10][C:11](=[O:12])[NH:13][CH:14]([CH3:15])[c:16]2[n:17][cH:18][c:19]([O:22][CH2:23][C:24]([F:25])([F:26])[F:27])[cH:20][cH:21]2)[cH:8][cH:9]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[Cl:38][CH2:39][Cl:40].[Na+:35].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1.[OH-:34].[OH2:41].[OH:36][OH:37]>>[CH:1]([CH2:2][OH:28])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([CH2:10][C:11](=[O:12])[NH:13][CH:14]([CH3:15])[c:16]2[n:17][cH:18][c:19]([O:22][CH2:23][C:24]([F:25])([F:26])[F:27])[cH:20][cH:21]2)[cH:8][cH:9]1

Participants

9

Reactant 8

HCID 784Hydrogen PeroxideHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6331BoraneHCID 6344DichloromethaneHCID 8028Tetrahydrofuran2×HCID 682508082-(4-prop-1-en-2-ylphenyl)-N-[1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide

Product 1

HCID 703119712-[4-(1-hydroxypropan-2-yl)phenyl]-N-[1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide

Sources & evidence

ORD record
ord-21943c6404a94564be99d2ec4f181531
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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