Tetrahydrofuran → tert-Butyl 5-(2-(1-amino-2-methylpropan-2-yl)-pyridin-4-yl)-4-methylthiazol-2-ylcarbamate
Reaction equation
[Al+3:2].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12]([NH:13][c:14]1[s:15][c:16](-[c:20]2[cH:21][c:22]([C:26]([CH3:27])([CH3:28])[C:29]#[N:30])[n:23][cH:24][cH:25]2)[c:17]([CH3:19])[n:18]1)=[O:31].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12]([NH:13][c:14]1[s:15][c:16](-[c:20]2[cH:21][c:22]([C:26]([CH3:27])([CH3:28])[CH2:29][NH2:30])[n:23][cH:24][cH:25]2)[c:17]([CH3:19])[n:18]1)=[O:31]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b17252729cd94d3ca1b467f0ce55ae7c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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