Tetrahydrofuran → Tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate

HRID 1219615Notes

Reaction equation

HRID 1219615 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[F:22][c:23]1[cH:24][cH:25][c:26]([N+:29](=[O:30])[O-:31])[cH:27][cH:28]1.[OH:15][CH:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:23]2[cH:24][cH:25][c:26]([N+:29](=[O:30])[O-:31])[cH:27][cH:28]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 9590p-FluoronitrobenzeneHCID 79341Piperidin-4-olHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Product 1

HCID 2794776Tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-937806ceff7e41beb79d7b25358ab2d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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