Trifluoroacetic acid → 2-Hydroxy-8-[2-(4-isopropyl-1,3-thiazol-2-yl)ethyl]-3-(1H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

HRID 1219629Notes

Reaction equation

HRID 1219629 reaction equation
[CH3:37][O:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[OH:1][c:2]1[n:3][c:4]2[n:5]([c:6](=[O:22])[c:7]1-[c:8]1[n:9][n:10][n:11]([CH2:13][c:14]3[cH:15][cH:16][c:17]([O:18][CH3:19])[cH:20][cH:21]3)[n:12]1)[cH:23][cH:24][c:25]([CH2:27][CH2:28][c:29]1[s:30][cH:31][c:32]([CH:34]([CH3:35])[CH3:36])[n:33]1)[cH:26]2.[OH:45][C:46]([C:47]([F:48])([F:49])[F:50])=[O:51]>>[OH:1][c:2]1[n:3][c:4]2[n:5]([c:6](=[O:22])[c:7]1-[c:8]1[nH:9][n:10][n:11][n:12]1)[cH:23][cH:24][c:25]([CH2:27][CH2:28][c:29]1[s:30][cH:31][c:32]([CH:34]([CH3:35])[CH3:36])[n:33]1)[cH:26]2

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 135724437HCID 135724437, compound

Product 1

HCID 1784398052-Hydroxy-8-[2-(4-isopropyl-1,3-thiazol-2-yl)ethyl]-3-(1H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

Sources & evidence

ORD record
ord-aee6811c484a4e198dedeb74e23efb3d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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