Dichloromethane → N-{7-[(1-methanesulfonyl-piperidin-4-ylmethyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-yl}-isobutyramide

HRID 1219698Notes

Reaction equation

HRID 1219698 reaction equation
[C:27]([CH:28]([CH3:29])[CH3:30])(=[O:31])[Cl:32].[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([CH2:11][N:12]([CH:13]2[CH2:14][c:15]3[cH:16][c:17]([NH2:23])[cH:18][cH:19][c:20]3[CH2:21][CH2:22]2)[CH2:24][CH2:25][CH3:26])[CH2:9][CH2:10]1.[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:33][CH2:34][Cl:35]>>[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([CH2:11][N:12]([CH:13]2[CH2:14][c:15]3[cH:16][c:17]([NH:23][C:27]([CH:28]([CH3:29])[CH3:30])=[O:31])[cH:18][cH:19][c:20]3[CH2:21][CH2:22]2)[CH2:24][CH2:25][CH3:26])[CH2:9][CH2:10]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 62325Isobutyryl chlorideHCID 81531DiisopropylethylamineHCID 21362805N-(1-methanesulfonyl-piperidin-4-ylmethyl)-N-propyl-1,2,3,4-tetrahydro-naphthalene-2,7-diamine

Product 1

HCID 21362784N-{7-[(1-methanesulfonyl-piperidin-4-ylmethyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-yl}-isobutyramide

Sources & evidence

ORD record
ord-e60bde5774d8441ca7250f858264d50b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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