1,2-Dichloroethane → TERT-BUTYL 4-(INDOLIN-1-YL)PIPERIDINE-1-CARBOXYLATE

HRID 1219995Notes

Reaction equation

HRID 1219995 reaction equation
[CH2:1]1[CH2:2][c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[NH:9]1.[CH3:24][C:25](=[O:26])[OH:27].[Cl:30][CH2:31][CH2:32][Cl:33].[Na+:29].[O:10]=[C:11]1[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1.[OH-:28]>>[CH2:1]1[CH2:2][c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[N:9]1[CH:11]1[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 923Sodium ionHCID 961HydroxideHCID 10328IndolineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 11449513TERT-BUTYL 4-(INDOLIN-1-YL)PIPERIDINE-1-CARBOXYLATE

Sources & evidence

ORD record
ord-2f7ba32c9b8748ed9667e22f14649e72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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