Bicarbonate Ion → 1,1-Dimethylethyl 4-azido-1-piperidinecarboxylate

HRID 1220222Notes

Reaction equation

HRID 1220222 reaction equation
[Br:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1.[C:21](=[O:22])([OH:23])[O-:24].[I-:20].[N-:16]=[N+:17]=[N-:18].[Na+:15].[Na+:19].[Na+:25].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[OH2:31]>>[CH:2]1([N:16]=[N+:17]=[N-:18])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ion3×HCID 962WaterHCID 6228DimethylformamideHCID 30165Iodide IonHCID 33558AzideHCID 15541517tert-Butyl 4-bromopiperidine-1-carboxylate

Product 1

HCID 114587941,1-Dimethylethyl 4-azido-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-ceeb585c9e2548afbb83c323a7102317
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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