N-methyl-2-pyrrolidone → 2-(4-Chloro-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-1-[4-(4-chloro-phenyl)-4-(pyrrolidine-1-carbonyl)-piperidin-1-yl]-ethanone
Reaction equation
[CH2:31]1[CH2:32][CH2:33][NH:34][CH2:35]1.[CH3:36][N:37]1[CH2:38][CH2:39][CH2:40][C:41]1=[O:42].[Cl:1][c:2]1[c:3]([C:27]([F:28])([F:29])[F:30])[n:4][n:5]([CH2:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][C:14]([C:17](=[O:18])[OH:19])([c:20]3[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[CH2:15][CH2:16]2)[c:6]1[CH3:7]>>[Cl:1][c:2]1[c:3]([C:27]([F:28])([F:29])[F:30])[n:4][n:5]([CH2:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][C:14]([C:17](=[O:18])[N:34]3[CH2:33][CH2:32][CH2:31][CH2:35]3)([c:20]3[cH:21][cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[CH2:15][CH2:16]2)[c:6]1[CH3:7]Participants
4
Sources & evidence
- ORD record
- ord-c6a260c55618434f88e6ef2c060a03f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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