Diisopropylethylamine → Hydrochloric Acid

HRID 1220720Notes

Reaction equation

HRID 1220720 reaction equation
[CH2:16]([N:17]([CH:18]([CH3:19])[CH3:20])[CH:21]([CH3:22])[CH3:23])[CH3:24].[Cl:25][CH2:26][CH2:27][CH2:28][N:29]1[CH2:30][C:31]2([c:35]3[cH:36][cH:37][c:38]([C:41]([F:42])([F:43])[F:44])[cH:39][cH:40]3)[CH2:32][CH:33]2[CH2:34]1.[c:1]1([CH3:15])[c:2](-[c:7]2[c:8](=[O:14])[nH:9][c:10](=[O:13])[nH:11][cH:12]2)[cH:3][cH:4][cH:5][cH:6]1>>[ClH:25].[c:1]1([CH3:15])[c:2](-[c:7]2[c:8](=[O:14])[nH:9][c:10](=[O:13])[n:11]([CH2:26][CH2:27][CH2:28][N:29]3[CH2:30][C:31]4([c:35]5[cH:36][cH:37][c:38]([C:41]([F:42])([F:43])[F:44])[cH:39][cH:40]5)[CH2:32][CH:33]4[CH2:34]3)[cH:12]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 3

HCID 81531DiisopropylethylamineHCID 221689845-(o-tolyl)Pyrimidine-2,4-diolHCID 722584093-(3-Chloropropyl)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexane

Product 2

HCID 313Hydrochloric AcidHCID 691359405-(2-Methylphenyl)-1-[3-[1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propyl]pyrimidine-2,4-dione

Sources & evidence

ORD record
ord-770c7cb353984bb4872f5e16795fae5d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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