Tetrahydrofuran → 8-Benzyl-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-2-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[CH:10]([OH:25])[CH2:11][CH2:12][CH:13]1[CH:14]([S:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)(=[O:23])=[O:24])[CH2:15]2.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[Li+:43].[c-:33]1[c:34]2[c:35]([cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]2([c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[CH:10]([OH:25])[CH2:11][CH2:12][CH:13]1[CH2:14][CH2:15]2Participants
5
Sources & evidence
- ORD record
- ord-8337450375a6431fa2f004c8d2e7d8a1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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