Methanol → 2-(4-(5-(4-(Difluoromethoxy)phenyl)pyrimidin-2-ylamino)phenyl)-3-hydroxypropanoic acid
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:39][OH:40].[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[cH:18][cH:19][c:20]([CH:23]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:29][OH:30])[cH:21][cH:22]3)[n:14][cH:15]2)[cH:8][cH:9]1)[F:31].[Li+:33].[OH-:32].[OH2:41].[OH2:42]>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[cH:18][cH:19][c:20]([CH:23]([C:24](=[O:25])[OH:26])[CH2:29][OH:30])[cH:21][cH:22]3)[n:14][cH:15]2)[cH:8][cH:9]1)[F:31]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-32ea7ff2b6524f10ba356d673e31dbfb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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