Tetrahydrofuran → 2-Isopropyl-3,6-dimethoxy-5-(3,3,3-trifluoro-propyl)-2,5-dihydro-pyrazine
Reaction equation
[CH2:14]([Li:15])[CH2:16][CH2:17][CH3:18].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[CH:1]([CH3:2])([CH3:3])[CH:4]1[N:5]=[C:6]([O:12][CH3:13])[CH2:7][N:8]=[C:9]1[O:10][CH3:11].[I:19][CH2:20][CH2:21][C:22]([F:23])([F:24])[F:25]>>[CH:1]([CH3:2])([CH3:3])[CH:4]1[N:5]=[C:6]([O:12][CH3:13])[CH:7]([CH2:20][CH2:21][C:22]([F:23])([F:24])[F:25])[N:8]=[C:9]1[O:10][CH3:11]Participants
6
Sources & evidence
- ORD record
- ord-60c9385fbe5c4f4a8eb1ddd79816359c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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