Hydrochloric Acid → 6-chloro-N-(4-ethoxyphenyl)-7-methylimidazo[1,2-b]pyridazin-8-amine

HRID 1223120Notes

Reaction equation

HRID 1223120 reaction equation
[Br:1][c:2]1[c:3]2[n:4]([n:5][c:6]([Cl:9])[c:7]1[CH3:8])[cH:10][cH:11][n:12]2.[CH3:14][CH2:15][O:16][c:17]1[cH:18][cH:19][c:20]([NH2:23])[cH:21][cH:22]1.[CH3:24][O:25][c:26]1[cH:27][cH:28][c:29]([NH2:30])[cH:31][cH:32]1.[CH3:39][N:40]1[CH2:41][CH2:42][CH2:43][C:44]1=[O:45].[ClH:13].[K+:33].[K+:34].[O-:35][C:36]([O-:37])=[O:38].[OH2:46]>>[c:2]1([NH:23][c:20]2[cH:19][cH:18][c:17]([O:16][CH2:15][CH3:14])[cH:22][cH:21]2)[c:3]2[n:4]([n:5][c:6]([Cl:9])[c:7]1[CH3:8])[cH:10][cH:11][n:12]2

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 7732P-AnisidineHCID 90764-EthoxyanilineHCID 13387N-methyl-2-pyrrolidoneHCID 19660Carbonate IonHCID 86611714HCID 86611714, compound

Product 1

HCID 866117156-chloro-N-(4-ethoxyphenyl)-7-methylimidazo[1,2-b]pyridazin-8-amine

Sources & evidence

ORD record
ord-c6512434837d4a5eb17417c54a89dcb3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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