Chloride → Ethyl 8-chloro-1-[(6-methylpyridin-3-yl)methyl]-4-oxo-1,4-dihydrocinnoline-3-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][n:9]2[n:10][c:11]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:12](=[O:20])[c:13]3[cH:14][cH:15][cH:16][c:17]([Cl:19])[c:18]23)[cH:6][n:7]1.[CH3:27][Zn+:28].[Cl-:26].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1.[OH2:29].[cH:35]1[cH:36][cH:37][c:38]([P:39]([Pd:40]([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[P:79]([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)[c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[cH:110][cH:111]1>>[c:2]1([CH3:27])[cH:3][cH:4][c:5]([CH2:8][n:9]2[n:10][c:11]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:12](=[O:20])[c:13]3[cH:14][cH:15][cH:16][c:17]([Cl:19])[c:18]23)[cH:6][n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f05a05307e48446695757a7ed4bfb66e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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