Dimethylformamide → 1-{2-Oxo-2-[4-(4-pyrimidin-2-yl-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-3-carboxylic acid [3-(4-fluoro-phenyl)-1H-indazol-5-yl]-amide
Reaction equation
[CH3:47][CH2:48][N:49]([CH2:50][CH3:51])[CH2:52][CH3:53].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][nH:10][c:11]3[cH:12][cH:13][c:14]([NH2:17])[cH:15][c:16]23)[cH:6][cH:7]1.[O:18]=[C:19]([CH2:20][N:21]1[CH2:22][CH:23]([C:26](=[O:27])[OH:28])[CH2:24][CH2:25]1)[N:29]1[CH2:30][CH2:31][N:32]([c:35]2[cH:36][cH:37][c:38](-[c:41]3[n:42][cH:43][cH:44][cH:45][n:46]3)[cH:39][cH:40]2)[CH2:33][CH2:34]1.[O:54]=[CH:55][N:56]([CH3:57])[CH3:58]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][nH:10][c:11]3[cH:12][cH:13][c:14]([NH:17][C:26]([CH:23]4[CH2:22][N:21]([CH2:20][C:19](=[O:18])[N:29]5[CH2:30][CH2:31][N:32]([c:35]6[cH:36][cH:37][c:38](-[c:41]7[n:42][cH:43][cH:44][cH:45][n:46]7)[cH:39][cH:40]6)[CH2:33][CH2:34]5)[CH2:25][CH2:24]4)=[O:27])[cH:15][c:16]23)[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1511b1004ef6440599d38210b6a8ec2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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