Toluene → 1-[3-[tert-butyl(dimethyl)silyl]oxycyclopentyl]-7-chloro-3-(4-ethylphenyl)-4H-pyrimido[4,5-d]pyrimidin-2-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH:9]([NH:12][c:13]2[n:14][c:15]([Cl:29])[n:16][cH:17][c:18]2[CH2:19][NH:20][c:21]2[cH:22][cH:23][c:24]([CH2:27][CH3:28])[cH:25][cH:26]2)[CH2:10][CH2:11]1)([CH3:30])[CH3:31].[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[CH3:53][N:54]([CH3:55])[c:56]1[cH:57][cH:58][n:59][cH:60][cH:61]1.[Cl:39][C:40]([Cl:41])=[O:42].[Cl:50][CH2:51][Cl:52]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH:9]([N:12]2[c:13]3[n:14][c:15]([Cl:29])[n:16][cH:17][c:18]3[CH2:19][N:20]([c:21]3[cH:22][cH:23][c:24]([CH2:27][CH3:28])[cH:25][cH:26]3)[C:40]2=[O:42])[CH2:10][CH2:11]1)([CH3:30])[CH3:31]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7587c34fe86948c58c8055be88b7763b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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