Bromide ion → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(4,5-dimethyl-thiazole-2-carbonyl)-1H-quinolin-4-one
Reaction equation
[Br-:13].[Br-:15].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:16][O:17][N:18]([C:19](=[O:20])[c:21]1[cH:22][n:23]([CH2:32][c:33]2[n:34][c:35]([Br:39])[cH:36][cH:37][cH:38]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]2[c:30]1=[O:31])[CH3:40].[CH3:1][c:2]1[n:3][cH:4][s:5][c:6]1[CH3:7].[CH3:8][CH2:9][CH2:10][CH2:11][Li:12].[Mg+2:14].[cH:46]1[n:47][cH:48][s:49][cH:50]1>>[CH3:1][c:2]1[n:3][c:4]([C:19](=[O:20])[c:21]2[cH:22][n:23]([CH2:32][c:33]3[n:34][c:35]([Br:39])[cH:36][cH:37][cH:38]3)[c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]3[c:30]2=[O:31])[s:5][c:6]1[CH3:7]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3f0ab480340e46afa9ede10a6bc7682e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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