Acetic Acid → 4-(4-Trifluoromethyl-benzyl)-4H-thieno[3,2-b]pyrrole-3-carboxylic acid

HRID 1225598Notes

Reaction equation

HRID 1225598 reaction equation
[C:34]([OH:35])(=[O:36])[CH3:37].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][s:7][c:8]2[c:9]1[n:10]([CH2:13][c:14]1[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1)[cH:11][cH:12]2.[CH3:24][OH:25].[Li+:28].[OH-:27].[OH2:26]>>[O:2]=[C:3]([OH:4])[c:5]1[cH:6][s:7][c:8]2[c:9]1[n:10]([CH2:13][c:14]1[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]1)[cH:11][cH:12]2

Participants

8

Reactant 7

HCID 176Acetic AcidHCID 887MethanolHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 67182634HCID 67182634, compound

Product 1

HCID 671836564-(4-Trifluoromethyl-benzyl)-4H-thieno[3,2-b]pyrrole-3-carboxylic acid

Sources & evidence

ORD record
ord-b6148a73c46d4a57be7f2e1634afc54b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…