Dimethylformamide → tert-butyl N-[4-[3-[1-[2-(1,3-dioxoisoindol-2-yl)ethyl]benzimidazol-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

HRID 1225869Notes

Reaction equation

HRID 1225869 reaction equation
[C:29]([CH3:30])([CH3:31])([CH3:32])[O:33][C:34](=[O:35])[NH:36][CH:37]([CH2:38][C:39](=[O:40])[OH:41])[CH2:42][c:43]1[cH:44][c:45]2[cH:46][cH:47][cH:48][cH:49][c:50]2[cH:51][cH:52]1.[CH3:53][N:54]1[CH2:55][CH2:56][O:57][CH2:58][CH2:59]1.[NH:1]1[CH2:2][CH:3]([c:7]2[n:8][c:9]3[c:10]([n:11]2[CH2:12][CH2:13][N:14]2[C:15](=[O:24])[c:16]4[cH:17][cH:18][cH:19][cH:20][c:21]4[C:22]2=[O:23])[cH:25][cH:26][cH:27][cH:28]3)[CH2:4][CH2:5][CH2:6]1.[O:84]=[CH:85][N:86]([CH3:87])[CH3:88].[P-:60]([F:61])([F:62])([F:63])([F:64])([F:65])[F:66].[n:67]1([O:68][C:69]([N:70]([CH3:71])[CH3:72])=[N+:73]([CH3:74])[CH3:75])[c:76]2[n:77][cH:78][cH:79][cH:80][c:81]2[n:82][n:83]1>>[N:1]1([C:39]([CH2:38][CH:37]([NH:36][C:34]([O:33][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:35])[CH2:42][c:43]2[cH:44][c:45]3[cH:46][cH:47][cH:48][cH:49][c:50]3[cH:51][cH:52]2)=[O:40])[CH2:2][CH:3]([c:7]2[n:8][c:9]3[c:10]([n:11]2[CH2:12][CH2:13][N:14]2[C:15](=[O:24])[c:16]4[cH:17][cH:18][cH:19][cH:20][c:21]4[C:22]2=[O:23])[cH:25][cH:26][cH:27][cH:28]3)[CH2:4][CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 533979213-(Boc-amino)-4-(2-naphthyl)butyric AcidHCID 667869112-(2-(2-(piperidin-3-yl)-1H-benzo[d]imidazol-1-yl)ethyl)isoindoline-1,3-dione

Product 1

HCID 77191068tert-butyl N-[4-[3-[1-[2-(1,3-dioxoisoindol-2-yl)ethyl]benzimidazol-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-5d011ea56fcf47e6a91901567f8330ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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