Tetrahydrofuran → Methyl 2-{3-[2-(trifluoromethyl)phenoxy]pyrrolidin-1-yl}-1,3-thiazole-5-carboxylate
Reaction equation
[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[F:16][C:17]([c:18]1[c:19]([OH:24])[cH:20][cH:21][cH:22][cH:23]1)([F:25])[F:26].[O:46]=[C:47]([O:48][CH2:49][CH3:50])[N:51]=[N:52][C:53]([O:54][CH2:55][CH3:56])=[O:57].[OH:1][CH:2]1[CH2:3][N:4]([c:7]2[s:8][c:9]([C:12](=[O:13])[O:14][CH3:15])[cH:10][n:11]2)[CH2:5][CH2:6]1.[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[O:1]([CH:2]1[CH2:3][N:4]([c:7]2[s:8][c:9]([C:12](=[O:13])[O:14][CH3:15])[cH:10][n:11]2)[CH2:5][CH2:6]1)[c:19]1[c:18]([C:17]([F:16])([F:25])[F:26])[cH:23][cH:22][cH:21][cH:20]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-fdb997ed32a14aa8bd7206d6aaa3d853
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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