Hydrochloric Acid → 2-[(4-Benzhydryl-1-piperazinyl)methyl]-6-morpholino-1,2,3,4-tetrahydro-1-naphthalenol

HRID 1226362Notes

Reaction equation

HRID 1226362 reaction equation
[BH4-:81].[C:39](=[O:40])([O-:41])[OH:42].[CH3:83][OH:84].[CH3:85][CH2:86][OH:87].[CH:20]([N:21]1[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1)([c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1)[c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[CH:44]([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)([c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[N:57]1[CH2:58][CH2:59][N:60]([CH2:63][CH:64]2[C:65](=[O:80])[c:66]3[cH:67][cH:68][c:69]([N:74]4[CH2:75][CH2:76][O:77][CH2:78][CH2:79]4)[cH:70][c:71]3[CH2:72][CH2:73]2)[CH2:61][CH2:62]1.[ClH:19].[ClH:1].[Na+:43].[Na+:82].[O:2]1[CH2:3][CH2:4][N:5]([c:6]2[cH:7][c:8]3[c:9]([cH:10][cH:11]2)[C:12](=[O:13])[CH2:14][CH2:15][CH2:16]3)[CH2:17][CH2:18]1>>[CH:44]([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)([c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[N:57]1[CH2:58][CH2:59][N:60]([CH2:63][CH:64]2[CH:65]([OH:80])[c:66]3[cH:67][cH:68][c:69]([N:74]4[CH2:75][CH2:76][O:77][CH2:78][CH2:79]4)[cH:70][c:71]3[CH2:72][CH2:73]2)[CH2:61][CH2:62]1

Participants

10

Reactant 9

HCID 313Hydrochloric Acid2×HCID 702EthanolHCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 28123BorohydrideHCID 70048BenzhydrylpiperazineHCID 131795016-morpholino-3,4-dihydronaphthalen-1(2H)-oneHCID 203431782-[(4-benzhydryl-1-piperazinyl)methyl]-6-morpholino-3,4-dihydro-1(2H)-naphthalenone

Product 1

HCID 131795422-[(4-Benzhydryl-1-piperazinyl)methyl]-6-morpholino-1,2,3,4-tetrahydro-1-naphthalenol

Sources & evidence

ORD record
ord-71692ca0abf34ea4b32d44a813528edd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…